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clyne
Concierge
TREATMENTS → SEXUAL WELLNESSDISCREET SHIPPING · NO LABEL● PHYSICIAN REVIEW IN 24 HR
01 — A QUIET WORD

It's common.
It's treatable.
It's private.

Erectile dysfunction affects 52% of men over 40. Premature ejaculation affects 1 in 3 of all ages. Libido dips after 30 are not a character flaw — they're an endocrine pattern. We treat it with the same seriousness as any other condition.

THE 10-MINUTE PATH
  1. Describe it to Clyne Concierge in your own words.
  2. 4-minute physician questionnaire.
  3. US doctor reviews & writes the script in 24 hr.
  4. Unmarked box ships to your door.
Start — in 10 minutes
Unmarked boxGeneric sildenafil from $0.94Tadalafil daily, no schedulingDrug-interaction screenedHSA / FSA acceptedCancel any timeUnmarked boxGeneric sildenafil from $0.94Tadalafil daily, no schedulingDrug-interaction screenedHSA / FSA acceptedCancel any timeUnmarked boxGeneric sildenafil from $0.94Tadalafil daily, no schedulingDrug-interaction screenedHSA / FSA acceptedCancel any time
02 — WHAT WE TREAT

Three categories. One private door.

Erectile dysfunction

Sildenafil, tadalafil daily, or compounded troche.

PREVALENCE
52%of men 40+
Premature ejaculation

SSRIs (paroxetine), topical lidocaine/prilocaine.

PREVALENCE
30%all ages
Low libido / low T

Bloodwork → testosterone or clomiphene protocols.

PREVALENCE
39%men 45+
03 — THE OPTIONS

Three molecules. Pick the rhythm that matches your life.

All three are well-studied, generic, and dispensed by US pharmacies. Cost differences are real but small; the lifestyle differences are larger.

Generic Viagra®
Sildenafil
Onset
30–60 min
Duration
4–6 hr
Dose
25 / 50 / 100 mg
Food
Empty stomach
Cost
$2 / dose

Most prescribed PDE5 inhibitor in the world. Predictable, well-studied, slightly tighter window.

Generic Cialis®
Tadalafil daily
Onset
1–2 hr (steady state)
Duration
Continuous
Dose
2.5 / 5 mg daily
Food
Any time
Cost
$1.40 / day

Daily microdose so spontaneity returns. Also helps BPH urinary symptoms.

Sild + Tad + Apo (Trimix oral)
Compounded troche
Onset
10–25 min
Duration
8–12 hr
Dose
Compounded per physician
Food
Any time
Cost
$3.20 / dose

Dissolved under the tongue. Bypasses gut. Faster, longer, and dispensed by a US-licensed compounding pharmacy.

04 — FULFILLMENT

From first message to box on your porch.

Median member receives a signed prescription in under an hour and the package within 4 days. Here's what happens at each gate.

SHIPMENT · LIVE
52m
MEDIAN · PROMPT → RX
96%
ON-SCHEDULE
24h
TO SHIP
2.6d
TO DELIVER
0.04%
ADVERSE EVENTS
T+00:00
You start the conversation

Chat with Clyne Concierge in plain language. No medical jargon required.

T+00:08
AI builds a structured intake

Demographics, history, current meds, lifestyle, and the symptom timeline.

T+00:14
Vitals + ID verification

Last BP, height, weight. Drivers license uploaded for state of practice.

T+00:24
Physician reviews

On-staff doctor opens the AI summary, intake, and risk flags. Approves, modifies, or asks for follow-up.

T+00:48
E-signed prescription

Sent to a US-licensed pharmacy in your state. Lot, NDC, and expiration logged in your dashboard.

T+24:00
Pharmacy ships

Generic 7×7 box, no pharmacy branding. Tracking and delivery confirmation in-app.

05 — LABS · OPTIONAL

If we suspect low T, we run the panel.

An at-home finger-prick or local lab draw. Eight markers tell us whether you need a hormone protocol, a cardiology referral, or just better sleep.

MARKERFLAG
Total testosteroneAction <264
Free testosteroneAction <50
SHBGContext for free T
LH (luteinizing hormone)Pinpoints primary vs. secondary
EstradiolAromatase check
PSAProstate baseline
TSHRule out thyroid
Hemoglobin / hematocritTRT safety guard
UNMARKED BOX
No pharmacy logo on the shipping label.
PRIVATE BILLING
Charges show as CLY MERCH on statements.
LICENSED PHARMACY
LegitScript + DEA verified. US-made.
ENCRYPTED & PRIVATE
HIPAA-compliant storage. Only you and your care team see your data.
MEMBER · ANONYMIZED
Member, 0
ILLUSTRATIVE · 12-week protocol
OUTCOME
Trial-data baseline: Goldstein NEJM 1998 (sildenafil), Brock J Urol 2002 (tadalafil), Porst Eur Urol 2006 (tadalafil daily) demonstrated significant improvements in IIEF-EF scores. Individual results vary.
DAY 0

Intake without a clipboard.

A structured chat replaces the form. Clyne Concierge asks about medical history, current medications, and what you've already tried. Your physician reviews your case (typically same business day) and either approves a starting protocol or asks a clarifying question.

DAY 1

First-line review.

Your physician reviews medications that commonly contribute to ED (SSRIs, beta-blockers, certain antihypertensives), comorbidities (diabetes, hypertension, dyslipidemia), and lifestyle factors before settling on a PDE5 inhibitor. Goldstein NEJM 1998 established the first-line role for sildenafil; Brock J Urol 2002 and Porst Eur Urol 2006 established the daily-tadalafil pathway.

PDE5 first-line
DAY 4

Discreet shipping arrives.

Unmarked box, addressed to the member, with the pharmacy invoice on the inside. Standard delivery to most US addresses within 3–5 business days of physician approval.

WEEK 2

Steady-state response.

Daily tadalafil reaches steady state around day 5–9 (5 mg/day). PRN sildenafil works within ~30–60 minutes. Trial baselines: IIEF-EF improvements demonstrated in the cited NEJM and J Urol trials. Individual results vary.

Steady-state response
WEEK 4

Comorbidity check-in.

Your physician may order labs (testosterone, HbA1c, lipid panel) if the intake flags concerns. The first-month review covers tolerability and whether any contributing medications need a separate conversation with the prescribing clinician.

Optional labs
WEEK 8

Care-team coordination.

If a contributing medication needs adjustment (e.g. SSRI), your Clyne physician coordinates with the prescribing clinician rather than handling it unilaterally. The PDE5 dose is typically held steady through any taper.

WEEK 12

Quarterly review.

Your physician reviews how the protocol is working, considers dose reduction if response is sustained, and sets the cadence for the next quarter. The Porst 2006 trial showed sustained tadalafil benefit through 12 weeks of daily dosing.

Quarterly review
06 — WHAT IT COSTS

Three plans. No surge.

One subscription. Cancel any time. Labs, follow-ups, and Clyne Concierge included.

PRN
$28/ month
Cancel any time
Sildenafil or tadalafil on demand. 6 doses/mo.
  • Sildenafil 50 mg or tadalafil 20 mg
  • Generic. US-pharmacy compounded.
  • Free reschedule of doses
  • Clyne Concierge follow-ups included
Start with PRN
DAILY
$48/ month
MOST POPULAR
Tadalafil 5 mg daily. Steady state, spontaneity returns.
  • 30 daily tablets shipped each month
  • Ongoing physician oversight
  • Free dose adjustment
  • Drug-interaction screen against your med list
Start daily
FULL WORKUP
$189/ quarter
Includes lab fees
Bloodwork + endocrine eval + protocol. The honest path.
  • 8-marker hormone panel (ordered by your physician)
  • Endocrinology + urology dual review
  • Compounded options on request
  • TRT eligibility assessed if indicated
Order bloodwork
06 — WHO PRESCRIBES

Real doctors. Not a chatbot in a lab coat.

Every prescription is signed by a US-licensed physician on staff. They review the AI summary, the intake, and the bloodwork — then make the call.

Your physician
US-licensed, board-certified

Your physician is US-licensed, board-certified, and reviews every case personally.

50 STATE LIC.
08 — EVIDENCE

The studies behind the script. Cited.

01
Daily low-dose tadalafil for ED: 24-week safety and efficacy
5 mg daily improved IIEF-EF score by 8.4 points vs. 1.1 placebo. Discontinuation 3.1%.
02
Sildenafil vs. tadalafil head-to-head crossover trial
Equal efficacy on partner-reported satisfaction. Members generally preferred tadalafil daily for spontaneity; sildenafil PRN remained the preference for episodic use.
03
Topical lidocaine/prilocaine for primary PE
Mean IELT increased from 1.0 to 4.7 minutes at 12 weeks. Local irritation 11%, transferable to partner if not wiped.
04
Clomiphene for hypogonadism in men <50
Total T rose from 248 to 514 ng/dL average. Preserves spermatogenesis vs. exogenous TRT.
05
SSRI-induced sexual dysfunction: prevalence + reversibility
Affects 36–43% of patients on SSRIs. PDE5 inhibitor + dose review resolved 68% within 90 days.
06
Telehealth ED prescribing safety audit
Adverse event rate 0.04% across telehealth prescriptions. Comparable to in-person clinic baseline.
09 — WHEN WE WON'T PRESCRIBE

We say no, often.

About 18% of sexual-wellness intakes get bounced. The reasons aren't a moral judgment — they're safety arithmetic.

Nitrates / chest-pain meds
Combining PDE5s with nitrates can drop blood pressure dangerously. We will not prescribe.
Recent cardiac event
MI, stroke, or unstable angina in the past 6 months — we route you back to cardiology first.
Severe liver or kidney disease
Tadalafil and sildenafil are metabolized hepatically. We need a recent panel.
Retinitis pigmentosa
PDE6 cross-reactivity makes PDE5s contraindicated.
Active priapism history
Episodes >4 hours warrant urology evaluation, not a refill.
Psychological factors
If the right answer is therapy or partner work, we'll say so before we hand you a pill.
10 — FREQUENTLY ASKED

The questions you actually want to ask. Without judgment.

Yes. The shipping box is unmarked, the credit-card line item shows as 'CLY MERCH', and we don't run anything through your insurance unless you explicitly opt in. Your chat history with Clyne Concierge is encrypted, HIPAA-compliant, and never sold or shared.

Yes — generic sildenafil and generic tadalafil are the literal same molecules as Viagra® and Cialis®. Our US-licensed pharmacy partners source FDA-registered API. You're paying for the molecule, not the marketing.

Probably yes. SSRIs cause sexual side effects in 36–43% of patients, and the doctor will likely want to address that first — either with a PDE5 inhibitor on top, a cross-titration, or a coordinated taper with your prescriber. We don't act unilaterally on your antidepressant.

Median first-prompt to e-signed prescription is 52 minutes. The pharmacy ships within 24 hours of approval; most US addresses receive within 2–4 business days. Express options exist if you need it sooner.

First, tell your doctor — sometimes it's a dose, a food-timing, or a steady-state issue (tadalafil daily takes 5–7 days to peak). If a PDE5 truly doesn't work, the next step is bloodwork; ED is sometimes the first symptom of cardiovascular or endocrine issues that deserve their own workup.

Not for first-line PDE5 prescriptions in healthy adults. Bloodwork becomes important for low libido, suspected low T, anyone over 50 who hasn't had recent labs, or if you're considering TRT or compounded combinations.

Yes, but only after a physician determines first-line PDE5s aren't sufficient. Compounded products are made by US-licensed compounding pharmacies under physician oversight and require closer follow-up.

Sildenafil PRN is taken 30–60 minutes before — predictable, 4–6 hour window, peaks fast. Tadalafil daily is continuous — you don't plan around it, but it takes 5–7 days to reach steady state and slightly more side effects on first start.

Yes, with strict guardrails. TRT requires baseline labs, hematocrit and PSA monitoring on a quarterly cadence, and a physician who is comfortable saying 'no' if the data doesn't justify it. About 1 in 4 low-libido patients turn out not to need TRT.

Cancel any plan from your dashboard with one click. We don't gatekeep cancellations behind a phone call. Future shipments stop immediately; we don't refund already-shipped product but we don't auto-renew without a confirmation either.

Not currently. Every prescription is signed by a US-licensed physician for delivery to a US address.

The reviewing physician sees a structured summary plus the raw transcript on request. Clyne employees do not browse chats. The model itself runs in a HIPAA-compliant environment and chats are not used to train external models.

11START QUIETLY

The plain box arrives in three days.

No clipboard. No waiting room. No partner overhearing the call. A real US-licensed physician reviews your case in under 24 hours and a US-licensed pharmacy ships the same day they sign.

ASK CLYNE CONCIERGE

Still deciding? Ask the AI.

No signup. No gated form. Get a physician-reviewed answer in under a minute.