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Concierge
SCIENCE · TRANSPARENCYMODEL CARD · TRIAL TAPE · ERRATAUPDATED Q2 2026
00 — SHOW YOUR WORK

Trust is earned with receipts.

Most telehealth marketing reads like a vibe board. We'd rather you read the system prompt, the trial citations, and the editorial standards. Then decide if we deserve your trust.

01 — CLINICAL EVIDENCE

Every claim has a citation.

We index 27,000+ peer-reviewed abstracts. Our physicians review every Rx with the trial in front of them. If we can't cite it, we won't say it.

INDEXED ABSTRACTS27,418
PARTICIPANTS · GLP-1 TRIALS23,415
RX HAS A CITATION100%
02 — AI MODEL CARD

Open about the system.

Claude 4.5 Sonnet, retrieval-augmented over the trial index, with hard escalation triggers and physician override on every prescription. Nothing in the chat ever trains the model.

AVG TIME TO FIRST TOKEN1.2 s
ESCALATION RATE TO PHYSICIAN0.3%
PATIENT DATA TRAINED ONZero
03 — EDITORIAL STANDARDS

We hold ourselves to NEJM rules.

Conflicts disclosed. Authorship signed. Numbers cited. We never market off-label uses, hide trial nuances, or rebrand bro-science as protocol.

ON-STAFF MDs11
EXTERNAL AUDITQuarterly
ERRATA LOGPublic
01 — TRIAL TAPE

A live citation feed.

UPDATED WHEN A NEW TRIAL CHANGES PROTOCOL
TRIALSOURCE
STEP 1Semaglutide 2.4 mg in obesity−14.9% body weight · 68 wkNEJM 2021
PIONEER 4Oral semaglutide vs liraglutide−15.1% body weight · 68 wkLancet 2023
SELECTSemaglutide & cardiovascular outcomes−20% MACE riskNEJM 2023
Trial of finasteride for AGA5α-reductase blockade+86% terminal hair · 12 moJAAD 1998
Tadalafil PD-5 inhibitorED in men 40++57% successful intercourseJAMA 2003
Horvath DNAm clockEpigenetic age estimationr=0.96 vs chronological ageGenome Biol 2013
02 — MODEL CARD

The system prompt is not a secret.

SYSTEM_PROMPT

You are Clyne Concierge, a clinical assistant for the Clyne telehealth platform. You speak with the
calm authority of a knowledgeable friend, not a hospital pamphlet. Cite trials, percentages,
and mechanisms when you have them. Be honest about limits — note when something is medical
advice vs. information. Never market off-label uses. Always escalate to a US-licensed physician
for prescriptions, anything new about a controlled substance, or anything outside your guardrail
catalogue. Do not train on this conversation.
MODEL
Claude 4.5 Sonnet
RETRIEVAL
Vector search, 27k abstracts
GUARDRAILS
Hard escalation on Rx + controlled substances
PRIVACY
Zero training on patient data
03 — EDITORIAL STANDARDS

We hold ourselves to journal rules.

AUTHORSHIP
Every clinical page lists the reviewing physician + license #.
CONFLICTS
Compounding pharmacies, manufacturers, employees: all disclosed.
OFF-LABEL
We never market off-label. Off-label Rx is physician-directed, in writing.
ERRATA
If we get something wrong, the correction goes on the page in 48 hours.
TRIAL NUANCE
We surface dropouts, side-effect profiles, and trial demographics.
AUDIT
Quarterly external review by a board-certified academic clinician.
ERRATA · NONE OPEN
Spotted something we got wrong?
Mail it to science@clyne.com. Confirmed errors are corrected within 48 hours and logged here.
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